24 September 2013In the 80s, what we now know as line and wrinkle injectables had an almost entirely different use – until Jean and Alistair Carruthers came along. The original use was to treat people suffering from crossed or improperly-aligned eyes. But the Canadian couple discovered the toxin’s cosmetic properties when they noticed their patients’ frown lines disappeared or softened during treatment.After being cleared for use in the beauty industry in 2002 it took the world by storm – in the US alone, there are now more than five million treatments every year. Unfortunately for the husband and wife, they missed out on the opportunity to patent the drug – something Jean has never been too worried about. “I missed out on a fortune, but we have had the most enriching experience using it on patients over the years,” she said.